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Pacers vs. Bulls prediction: Why Chicago is favored to win Friday's NBA matchup [12/5/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Indiana Pacers vs Chicago Bulls predictions for NBA Friday.
The Chicago Bulls will square off with the Indiana Pacers in NBA action at United Center on Friday, beginning at 8:00PM ET.
Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Bulls as the most likely winner of the Pacers vs. Bulls game.
This prediction follows the latest NBA Injury Report, which suggests the Bulls lineup will feature stars like Coby White, Josh Giddey and Nikola Vucevic, while the Pacers will rely on Pascal Siakam, Bennedict Mathurin and Andrew Nembhard.
This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pacers vs. Bulls prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Friday's NBA game between the Pacers and Bulls 10,000 times as part of our NBA predictions coverage.
Our independent predictive model currently gives the Bulls a 63% chance of beating the Pacers. Our predicted final score has the Bulls winning 119-116.
According to our model, the Pacers (+4.5) have a 52% chance of covering the spread, while the 236.5-point over/under has a 52% chance of staying under.
Pacers vs. Bulls odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Pacers | Bulls |
|---|---|---|
| Spread | +4.5 (-110) | -4.5 (-108) |
| Moneyline | +164 | -186 |
| Total | o236.5 (-110) | u236.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Pacers vs. Bulls picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +4.5 | -110 |
| Moneyline | Pacers | +164 |
| Total | Under 236.5 | -105 |
According to our best NBA bets for Friday, the top play to make on this game is Under 236.5 total points.
Pacers vs. Bulls player props
Betting on Pacers vs. Bulls NBA player props? We use the best information available to project how each team's leading players will perform at United Center.
Pascal Siakam is expected to lead the Pacers with 23 points, 7 rebounds and 4 assists, while Coby White is projected to have 24 points, 3 rebounds and 4 assists for the Bulls.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Pacers prediction
Our model's projected player stats for the Pacers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 23 | 7 | 4 | 1 | 43 |
| B. Mathurin | 21 | 6 | 3 | 2 | 37 |
| Andrew Nembhard | 15 | 3 | 6 | 2 | 33 |
| T.J. McConnell | 13 | 4 | 6 | 0 | 30 |
| Jay Huff | 12 | 5 | 2 | 2 | 29 |
Bulls prediction
Projected points, rebounds, assists and three-pointers made for the Bulls:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Coby White | 24 | 3 | 4 | 2 | 37 |
| Josh Giddey | 20 | 10 | 8 | 2 | 50 |
| Nikola Vucevic | 18 | 10 | 4 | 2 | 40 |
| Matas Buzelis | 15 | 5 | 2 | 2 | 32 |
| Ayo Dosunmu | 15 | 3 | 4 | 2 | 30 |
Pacers vs. Bulls game-day updates and essential details
Friday's action between the Bulls and Pacers at United Center is scheduled to start at 8:00PM ET.
- Who: Indiana Pacers vs. Chicago Bulls
- Date: Friday, December 5, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: United Center
Conclusion
We predict the Bulls, with a 63% win probability, will likely beat the Pacers on Friday, with Josh Giddey projected for a game-high 50 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pacers vs. Bulls insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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