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Illinois State vs. Murray State prediction: Why Murray State is favored to win men's college basketball matchup [1/28/2026]

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Written by Mac Douglass

Get Illinois State vs Murray State predictions for college basketball Wednesday.

Illinois State-Murray State Predictions and Game Preview.
Illinois State vs. Murray State men's college basketball prediction for Wednesday, January 28, 2026.

Murray State will square off with Illinois State in men's college basketball action at CFSB Center on Wednesday, starting at 9:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Murray State as the most likely winner of the Illinois State vs. Murray State game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Illinois State vs. Murray State prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Illinois State and Murray State 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Murray State a 61% chance of defeating Illinois State. Our predicted final score has Murray State winning 80-77.

According to our model, Murray State (-2.5) has a 56% chance of covering the spread, while the 159.5-point over/under has an equal 50-50 chance of hitting.

 

Illinois State vs. Murray State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Illinois State Murray State
Spread +2.5 (-102) -2.5 (-118)
Moneyline +138 -160
Total o159.5 (-105) u159.5 (-115)

All odds are correct at the time of publication and are subject to change.

Illinois State vs. Murray State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Murray State -2.5 -118
Moneyline Murray State -160
Total Over 159.5 -105

According to our men's college basketball best bets, the top play to make on this game is Murray State -2.5 at the spread.

 

Illinois State vs. Murray State game-day updates and essential details

Wednesday's men's college basketball matchup between Murray State and Illinois State at CFSB Center is scheduled to commence at 9:00 PM ET.

  • Who: Illinois State vs. Murray State
  • Date: Wednesday, January 28, 2026
  • Time: 9:00 PM ET/6:00PM PT
  • Venue: CFSB Center

Conclusion

We predict Murray State, with a 61% win probability, will likely beat Illinois State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Illinois State vs. Murray State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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