Illinois-Chicago vs. Charlotte prediction: Why Charlotte is favored to win men's college basketball matchup [12/21/2025]

Charlotte will face Illinois-Chicago in men's college basketball action at Dale F. Halton Arena on Sunday, beginning at 2:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Charlotte as the most likely winner of the Illinois-Chicago vs. Charlotte game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Illinois-Chicago vs. Charlotte prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball game between Illinois-Chicago and Charlotte 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Charlotte a 55% chance of defeating Illinois-Chicago. Our predicted final score has Charlotte winning 69-68.

According to our model, Illinois-Chicago (+2.5) has a 58% chance of covering the spread, while the over/under total of 137.5 points has an equal 50-50 chance of hitting.

Illinois-Chicago vs. Charlotte odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Illinois-Chicago vs. Charlotte picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: