Illinois-Chicago vs. Charlotte prediction: Why Charlotte is favored to win men's college basketball matchup [12/21/2025]

Men's college basketball action continues on Sunday at 2:00 PM ET as Illinois-Chicago takes on Charlotte in men's college basketball action at Dale F. Halton Arena.

Based on the latest simulation results, Dimers' proven college basketball model gives Charlotte a slight edge with a 54% win probability over Illinois-Chicago.

This article offers further insights into Sunday's Illinois-Chicago vs. Charlotte matchup, including an expanded look at the predicted score, best bets and picks.

Illinois-Chicago vs. Charlotte prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Sunday's NCAA basketball game between Illinois-Chicago and Charlotte 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Charlotte a 54% chance of defeating Illinois-Chicago. Our predicted final score has Charlotte winning 69-68.

According to our model, Illinois-Chicago (+1.5) has a 58% chance of covering the spread, while the 137.5-point over/under has an equal 50-50 chance of hitting.

Illinois-Chicago vs. Charlotte odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Illinois-Chicago vs. Charlotte picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Illinois-Chicago +1.5 at the spread.

Illinois-Chicago vs. Charlotte game-day updates and essential details

Sunday's men's college basketball game between Charlotte and Illinois-Chicago at Dale F. Halton Arena is scheduled to start at 2:00 PM ET.

• Who: Illinois-Chicago vs. Charlotte
• Date: Sunday, December 21, 2025
• Time: 2:00 PM ET/11:00AM PT
• Venue: Dale F. Halton Arena

Conclusion

We predict Charlotte, with a 54% win probability, will likely beat Illinois-Chicago on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Illinois-Chicago vs. Charlotte insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.