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Houston vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [2/16/2026]

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Written by Mac Douglass

Get Houston vs Iowa State predictions for college basketball Monday.

Houston-Iowa State Predictions and Game Preview.
Houston vs. Iowa State men's college basketball prediction for Monday, February 16, 2026.

Iowa State will take on Houston in men's college basketball action at James H. Hilton Coliseum on Monday, starting at 9:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Iowa State as the most likely winner of the Houston vs. Iowa State game.

This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Houston vs. Iowa State prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Monday's NCAA basketball game between Houston and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 63% chance of beating Houston. Our predicted final score has Iowa State winning 71-68.

According to our model, Iowa State (-2.5) has a 56% chance of covering the spread, while the 137.5-point over/under has a 58% chance of going over.

 

Houston vs. Iowa State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Houston Iowa State
Spread +2.5 (-110) -2.5 (-110)
Moneyline +125 -125
Total o137.5 (-120) u137.5 (-110)

All odds are correct at the time of publication and are subject to change.

Houston vs. Iowa State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Iowa State -2.5 -110
Moneyline Iowa State -125
Total Over 137.5 -120

According to our best men's college basketball bets, the top play to make on this game is Iowa State to win.

 

Houston vs. Iowa State game-day updates and essential details

Monday's men's college basketball action between Iowa State and Houston at James H. Hilton Coliseum is scheduled to start at 9:00 PM ET.

  • Who: Houston vs. Iowa State
  • Date: Monday, February 16, 2026
  • Time: 9:00 PM ET/6:00PM PT
  • Venue: James H. Hilton Coliseum

Conclusion

We predict Iowa State, with a 63% win probability, will likely beat Houston on Monday.

AI and automation have enhanced this article to quickly deliver accurate Houston vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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