Rockets vs. Grizzlies prediction: Houston to win, Kevin Durant projected for big game in Wednesday's NBA matchup [11/5/2025]

The Memphis Grizzlies and Houston Rockets are scheduled to meet in NBA action at FedExForum on Wednesday, with tipoff at 8:00PM ET.

Based on updated simulations and today’s injury news, Dimers' proven NBA model projects the Rockets as the most likely winner of the Rockets vs. Grizzlies game.

This prediction follows the latest NBA Injury Report, which suggests the Grizzlies lineup will feature stars like Ja Morant, Jaren Jackson and Cedric Coward, while the Rockets will look to Kevin Durant, Alperen Sengun and Amen Thompson.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Rockets vs. Grizzlies prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the result of Wednesday's NBA matchup between the Rockets and Grizzlies 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Rockets a 72% chance of beating the Grizzlies. Our predicted final score has the Rockets winning 119-112.

According to our model, the Grizzlies (+7.5) have a 53% chance of covering the spread, while the over/under total of 232.5 points has a 52% chance of staying under.

Rockets vs. Grizzlies odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Rockets vs. Grizzlies picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Wednesday, the top play to make on this game is Grizzlies +7.5 at the spread.

Rockets vs. Grizzlies player props

NBA player props are a common way to wager on Wednesday's Houston vs. Memphis matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at FedExForum.

Kevin Durant is expected to lead the Rockets with 25 points, 5 rebounds and 4 assists, while Ja Morant is projected to have 24 points, 4 rebounds and 7 assists for the Grizzlies.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Rockets prediction

Our model's projected player stats for the Rockets are:

Grizzlies prediction

Projected points, rebounds, assists and three-pointers made for the Grizzlies:

Rockets vs. Grizzlies game-day updates and essential details

Wednesday's action between the Grizzlies and Rockets at FedExForum is scheduled to commence at 8:00PM ET.

• Who: Houston Rockets vs. Memphis Grizzlies
• Date: Wednesday, November 5, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: FedExForum

Conclusion

We predict the Rockets, with a 72% win probability, will likely beat the Grizzlies on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Rockets vs. Grizzlies insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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