Astros vs. Brewers Prediction: Houston Predicted to Win Wednesday's MLB Matchup [5/7/2025]

MLB action continues on Wednesday at 1:10PM ET as the Houston Astros square off with the Milwaukee Brewers at American Family Field.

The Brewers will send Quinn Priester (1-0, 5.79 ERA) to the mound, pitting him against Framber Valdez (1-4, 4.39 ERA) for the Astros.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Houston-Milwaukee game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Astros' chance of winning at 54%, with the Brewers at 46%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Astros vs. Brewers predictions page.

Brewers vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Astros and Brewers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Astros a 54% chance of beating the Brewers.

According to our model, the Brewers (+1.5) have a 59% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of going over.

Astros vs. Brewers Odds [5/7/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Brewers
Run Line	-1.5 (+135)	+1.5 (-155)
Moneyline	-130	+116
Total	o7.5 (-115)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Brewers Picks and Best Bets

Our model's biggest edge in today's Astros vs. Brewers matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Astros vs. Brewers Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Brewers and Astros at American Family Field is scheduled to begin at 1:10PM ET.

• Who: Houston Astros vs. Milwaukee Brewers
• Date: Wednesday, May 7, 2025
• Time: 1:10PM ET/10:10AM PT
• Venue: American Family Field

Dimers.com's in-depth preview of Wednesday's Astros vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Astros, with a 54% win probability, will likely beat the Brewers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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