Astros vs. Red Sox prediction: Boston favored to win Saturday's MLB matchup [5/2/2026]
Get Houston Astros vs Boston Red Sox predictions for MLB Saturday.

The Boston Red Sox and Houston Astros will lock horns in MLB action at Fenway Park on Saturday, starting at 4:10 PM ET.
Connelly Early (2-1, 2.84 ERA) will be on the bump for the Red Sox, up against Spencer Arrighetti (3-0, 2.00 ERA) for the Astros.
Based on the latest simulations, Dimers' proven MLB model predicts the Red Sox as the most likely winner of the Astros vs. Red Sox game.
This article offers an expanded analysis of Saturday's matchup, including best bets and picks.
Astros vs. Red Sox prediction: Who will win and cover?
Our leading predictive model gives the Red Sox a 55% chance of beating the Astros.
According to our model, the Astros (+1.5) have a 62% chance of covering the run line, while the over/under total of nine runs has a 51% chance of going over.
Astros vs. Red Sox odds [5/2/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Astros | Red Sox |
|---|---|---|
| Run Line | +1.5 (-175) | -1.5 (+150) |
| Moneyline | +120 | -140 |
| Total | o9 (-102) | u9 (-115) |
All odds are correct at the time of publication and are subject to change.
Astros vs. Red Sox picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | -175 |
| Moneyline | Astros | +120 |
| Total | Over 9 | -102 |
According to our MLB best bets, the top play to make on this game is Over 9 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Red Sox game-day updates and essential details
Saturday's MLB game between the Red Sox and Astros at Fenway Park is scheduled to begin at 4:10 PM ET.
- Who: Houston Astros vs. Boston Red Sox
- Date: Saturday, May 2, 2026
- Time: 4:10 PM ET/1:10PM PT
- Venue: Fenway Park
Conclusion
We predict the Red Sox, with a 55% win probability, will likely beat the Astros in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



