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Harvard vs. Boston University prediction: Harvard favored to win men's college basketball matchup [11/22/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Harvard vs Boston University predictions for college basketball Saturday.
Boston University will square off with Harvard in men's college basketball action at Mohegan Sun Arena on Saturday, commencing at 1:30PM ET.
Based on updated simulations, Dimers' proven college basketball model predicts Harvard as the most likely winner of the Harvard vs. Boston University game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Harvard vs. Boston University prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Harvard and Boston University 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Harvard a 65% chance of beating Boston University. Our predicted final score has Harvard winning 70-66.
According to our model, Boston University (+3.5) has a 55% chance of covering the spread, while the 136.5-point over/under has a 54% chance of staying under.
Harvard vs. Boston University odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Harvard | Boston University |
|---|---|---|
| Spread | -3.5 (-120) | +3.5 (-102) |
| Moneyline | -180 | +172 |
| Total | o136.5 (-110) | u136.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Harvard vs. Boston University picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Boston University +3.5 | -102 |
| Moneyline | Harvard | -180 |
| Total | Under 136.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Boston University +3.5 at the spread.
Harvard vs. Boston University game-day updates and essential details
Saturday's men's college basketball matchup between Boston University and Harvard at Mohegan Sun Arena is scheduled to commence at 1:30PM ET.
- Who: Harvard vs. Boston University
- Date: Saturday, November 22, 2025
- Time: 1:30PM ET/10:30AM PT
- Venue: Mohegan Sun Arena
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Conclusion
We predict Harvard, with a 65% win probability, will likely beat Boston University on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Harvard vs. Boston University insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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