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Guardians vs. Royals Prediction for MLB Wednesday [9/20/2023]

The Kansas City Royals and Cleveland Guardians are scheduled to meet in MLB action at Kauffman Stadium on Wednesday, starting at 2:10PM ET.

The Royals will start Zack Greinke (1-15, 5.39 ERA), while the Guardians have opted for Lucas Giolito (8-13, 4.59 ERA).

Dimers' top betting picks for Guardians vs. Royals, as well as game predictions and betting odds, are detailed in this article.


Who Will Win: Guardians vs. Royals

Based on advanced machine learning and data, Dimers.com has simulated Wednesday's Guardians-Royals MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Guardians a 57% chance of defeating the Royals.

More: Betting Analysis for Guardians vs. Royals

Guardians vs. Royals Odds [9/20]

  • Run Line: Royals +1.5 (-125), Guardians -1.5 (+115)
  • Moneyline: Royals +126, Guardians -148
  • Total: Over/Under 8.5 (-115/+100)

The Royals are currently +1.5 underdogs versus the Guardians, with -125 at BetMGM the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, PointsBet has the best odds currently on offer at +115.

FanDuel Sportsbook currently has the best moneyline odds for the Royals at +126, which means you can bet $100 to profit $126, earning a total payout of $226, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Guardians at -148, where you can risk $148 to win $100, for a total payout of $248, if they come out on top.

The Over/Under for total runs scored sits at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, while PointsBet currently has the best odds for the Under at +100.

As always, check out all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) have a 56% chance of covering the run line, while the 8.5-run Over/Under has a 52% chance of going Over.

More: Live Scores for All Major Sports

Best Bets: Guardians vs. Royals


Our best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every time.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the Royals moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen here at Dimers is one of the keys to being profitable in the long run.

Guardians vs. Royals Prediction

Dimers.com predicts that the Guardians are more likely to defeat the Royals at Kauffman Stadium on Wednesday.

This prediction is based on comprehensive data-driven analysis, with the Guardians having a 57% chance of winning after conducting 10,000 simulations of the game.

Click or tap on See Matchup for more information.


Dimers has full coverage of Wednesday's Guardians-Royals game, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this article for any changes to our betting insights before Guardians vs. Royals on Wednesday September 20, 2023.


Guardians vs. Royals 2023

Wednesday's MLB game between the Royals and Guardians at Kauffman Stadium is scheduled to start at 2:10PM ET.

Looking to join an online sportsbook and start betting on MLB today? We've listed the best available welcome offers for every legal betting state.

Calling Our Shot ⚾️ Best Bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Make Smarter Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Guardians vs. Royals picks can help you make informed decisions, it's vital that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More MLB Predictions Like This?

So, you liked our Guardians vs. Royals betting analysis? Awesome. Did you know our MLB Betting News page has a comprehensive betting preview for every MLB matchup the second the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets. This allows us to write the most authoritative MLB betting previews and beat the public and the sportsbooks to the punch.

In addition to our leading MLB predictions, Dimers also offers the best MLB prop bets today, projecting home runs, RBIs, and more against the best odds available every day of the MLB season.

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-driven probabilities compared to the best odds available.


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