Grambling State vs. Southern Miss prediction: Southern Miss favored to win men's college basketball matchup [12/8/2025]

Southern Miss will square off with Grambling State in men's college basketball action at Reed Green Coliseum on Monday, beginning at 8:00PM ET.

Based on updated simulations, Dimers' proven college basketball model projects Southern Miss as the most likely winner of the Grambling State vs. Southern Miss game.

This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Grambling State vs. Southern Miss prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Monday's NCAA basketball matchup between Grambling State and Southern Miss 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Southern Miss a 78% chance of beating Grambling State. Our predicted final score has Southern Miss winning 75-67.

According to our model, the bookmakers have got it right, and Grambling State and Southern Miss each have a 50% chance of covering the spread, while the 141.5-point over/under has a 52% chance of going over.

Grambling State vs. Southern Miss odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Grambling State vs. Southern Miss picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Grambling State to win.

Grambling State vs. Southern Miss game-day updates and essential details

Monday's men's college basketball game between Southern Miss and Grambling State at Reed Green Coliseum is scheduled to start at 8:00PM ET.

• Who: Grambling State vs. Southern Miss
• Date: Monday, December 8, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Reed Green Coliseum

Conclusion

We predict Southern Miss, with a 78% win probability, will likely beat Grambling State on Monday.

AI and automation have enhanced this article to quickly deliver accurate Grambling State vs. Southern Miss insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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