Grambling State vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [11/6/2025]

Iowa State will face Grambling State in men's college basketball action at James H. Hilton Coliseum on Thursday, beginning at 8:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Iowa State as the most likely winner of the Grambling State vs. Iowa State game.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Grambling State vs. Iowa State prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Thursday's NCAA basketball matchup between Grambling State and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 99% chance of defeating Grambling State. Our predicted final score has Iowa State winning 86-57.

According to our model, Grambling State (+33.5) has a 55% chance of covering the spread, while the 143.5-point over/under has a 51% chance of going over.

Grambling State vs. Iowa State odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Grambling State vs. Iowa State picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Grambling State +33.5 at the spread.

Grambling State vs. Iowa State game-day updates and essential details

Thursday's men's college basketball matchup between Iowa State and Grambling State at James H. Hilton Coliseum is scheduled to begin at 8:00PM ET.

• Who: Grambling State vs. Iowa State
• Date: Thursday, November 6, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: James H. Hilton Coliseum

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Conclusion

We predict Iowa State, with a 99% win probability, will likely beat Grambling State on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Grambling State vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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