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Gonzaga vs. Oregon prediction: Gonzaga favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Gonzaga vs Oregon predictions for college basketball Sunday.

Gonzaga-Oregon Predictions and Game Preview.
Gonzaga vs. Oregon men's college basketball prediction for Sunday, December 21, 2025.

Oregon and Gonzaga are scheduled to meet in men's college basketball action at Moda Center on Sunday, starting at 6:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Gonzaga as the most likely winner of the Gonzaga vs. Oregon game.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Gonzaga vs. Oregon prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Gonzaga and Oregon 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Gonzaga a 75% chance of defeating Oregon. Our predicted final score has Gonzaga winning 80-73.

According to our model, Oregon (+12.5) has a 61% chance of covering the spread, while the over/under total of 155.5 points has a 53% chance of staying under.

 

Gonzaga vs. Oregon odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Gonzaga Oregon
Spread -12.5 (-110) +12.5 (-105)
Moneyline -1000 +680
Total o155.5 (-110) u155.5 (-105)

All odds are correct at the time of publication and are subject to change.

Gonzaga vs. Oregon picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Oregon +12.5 -105
Moneyline Oregon +680
Total Under 155.5 -105

According to our men's college basketball best bets, the top play to make on this game is Oregon to win.

 

Gonzaga vs. Oregon game-day updates and essential details

Sunday's men's college basketball game between Oregon and Gonzaga at Moda Center is scheduled to start at 6:00 PM ET.

  • Who: Gonzaga vs. Oregon
  • Date: Sunday, December 21, 2025
  • Time: 6:00 PM ET/3:00PM PT
  • Venue: Moda Center

Conclusion

We predict Gonzaga, with a 75% win probability, will likely beat Oregon on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Gonzaga vs. Oregon insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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