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Gardner-Webb vs. DePaul prediction: DePaul favored to win men's college basketball matchup [11/18/2025]

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Written by Dave Garofolo

Get Gardner-Webb vs DePaul predictions for college basketball Tuesday.

Gardner-Webb-DePaul Predictions and Game Preview.
Gardner-Webb vs. DePaul men's college basketball prediction for Tuesday, November 18, 2025.

DePaul will square off with Gardner-Webb in men's college basketball action at Wintrust Arena on Tuesday, beginning at 8:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts DePaul as the most likely winner of the Gardner-Webb vs. DePaul game.

This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Gardner-Webb vs. DePaul prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Gardner-Webb and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives DePaul a 96% chance of defeating Gardner-Webb. Our predicted final score has DePaul winning 87-65.

According to our model, the bookies have got it right, and Gardner-Webb and DePaul each have a 50% chance of covering the spread, while the 155.5-point over/under has a 53% chance of staying under.

 

Gardner-Webb vs. DePaul odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type Gardner-Webb DePaul
Spread +22.5 (-112) -22.5 (-105)
Moneyline +1800 -4000
Total o155.5 (-110) u155.5 (-110)

All odds are correct at the time of publication and are subject to change.

Gardner-Webb vs. DePaul picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread DePaul -22.5 -105
Moneyline DePaul -4000
Total Under 155.5 -110

According to our best men's college basketball bets, the top play to make on this game is Under 155.5 total points.

 

Gardner-Webb vs. DePaul game-day updates and essential details

Tuesday's men's college basketball game between DePaul and Gardner-Webb at Wintrust Arena is scheduled to begin at 8:00PM ET.

  • Who: Gardner-Webb vs. DePaul
  • Date: Tuesday, November 18, 2025
  • Time: 8:00PM ET/5:00PM PT
  • Venue: Wintrust Arena

Conclusion

We predict DePaul, with a 96% win probability, will likely beat Gardner-Webb on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Gardner-Webb vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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