Eastern Kentucky vs. Jacksonville State prediction: Jacksonville State favored to win men's college basketball matchup [12/17/2025]

Men's college basketball action continues on Wednesday at 7:00 PM ET as Eastern Kentucky takes on Jacksonville State in men's college basketball action at Pete Mathews Coliseum.

Based on the latest simulations, Dimers' proven college basketball model predicts Jacksonville State as the most likely winner of the Eastern Kentucky vs. Jacksonville State game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Eastern Kentucky vs. Jacksonville State prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Eastern Kentucky and Jacksonville State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Jacksonville State a 67% chance of beating Eastern Kentucky. Our predicted final score has Jacksonville State winning 72-68.

According to our model, Jacksonville State (-4.5) has a 51% chance of covering the spread, while the 142.5-point over/under has a 53% chance of staying under.

Eastern Kentucky vs. Jacksonville State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Eastern Kentucky vs. Jacksonville State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: