East Carolina vs. USF prediction: South Florida favored to win men's college basketball matchup [1/14/2026]

USF will take on East Carolina in men's college basketball action at Yuengling Center on Wednesday, starting at 7:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model projects South Florida as the most likely winner of the East Carolina vs. USF game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

East Carolina vs. USF prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between East Carolina and USF 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives South Florida a 95% chance of defeating East Carolina. Our predicted final score has South Florida winning 89-69.

According to our model, the bookmakers have got it right, and East Carolina and South Florida each have a 50% chance of covering the spread, while the over/under total of 156.5 points has a 53% chance of going over.

East Carolina vs. USF odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

East Carolina vs. USF picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: