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Duquesne vs. Villanova prediction: Villanova favored to win men's college basketball matchup [11/15/2025]

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Written by Dave Garofolo

Get Duquesne vs Villanova predictions for college basketball Saturday.

Duquesne-Villanova Predictions and Game Preview.
Duquesne vs. Villanova men's college basketball prediction for Saturday, November 15, 2025.

Villanova and Duquesne will lock horns in men's college basketball action at The William B. Finneran Pavilion on Saturday, starting at 8:00PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Villanova as the most likely winner of the Duquesne vs. Villanova game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Duquesne vs. Villanova prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between Duquesne and Villanova 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Villanova an 84% chance of defeating Duquesne. Our predicted final score has Villanova winning 80-70.

According to our model, Villanova (-10.5) has a 51% chance of covering the spread, while the over/under total of 151.5 points has a 52% chance of staying under.

 

Duquesne vs. Villanova odds

We have sourced the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type Duquesne Villanova
Spread +10.5 (-108) -10.5 (-110)
Moneyline +480 -600
Total o151.5 (-105) u151.5 (-115)

All odds are correct at the time of publication and are subject to change.

Duquesne vs. Villanova picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Villanova -10.5 -110
Moneyline Duquesne +480
Total Under 151.5 -115

According to our men's college basketball best bets, the top play to make on this game is Duquesne to win.

 

Duquesne vs. Villanova game-day updates and essential details

Saturday's men's college basketball matchup between Villanova and Duquesne at The William B. Finneran Pavilion is scheduled to begin at 8:00PM ET.

  • Who: Duquesne vs. Villanova
  • Date: Saturday, November 15, 2025
  • Time: 8:00PM ET/5:00PM PT
  • Venue: The William B. Finneran Pavilion

Sports betting deal available for Saturday

To make the most of Saturday's exciting day of sports, headlined by college football Saturday games, check out details on the latest Bet365 bonus code "DIMERS" that grants you $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict Villanova, with an 84% win probability, will likely beat Duquesne on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Duquesne vs. Villanova insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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