Duquesne vs. Saint Joseph's (PA) prediction: Duquesne favored to win men's college basketball matchup [1/7/2026]

Saint Joseph's (PA) will take on Duquesne, in what is expected to be a tight Men's College Basketball game, at Michael J. Hagan '85 Arena on Wednesday, beginning at 7:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model gives Duquesne a slight edge with a 54% win probability over Saint Joseph's (PA).

This article offers an expanded analysis of Wednesday's Duquesne vs. Saint Joseph's (PA) matchup, including an expanded look at the predicted score, best bets and picks.

Duquesne vs. Saint Joseph's (PA) prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Duquesne and Saint Joseph's (PA) 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Duquesne a 54% chance of beating Saint Joseph's (PA). Our predicted final score has Duquesne winning 75-74.

According to our model, Saint Joseph's (PA) (+1.5) has a 55% chance of covering the spread, while the 149.5-point over/under has a 52% chance of going over.

Duquesne vs. Saint Joseph's (PA) odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Duquesne vs. Saint Joseph's (PA) picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: