Duquesne vs. Loyola Chicago prediction: Duquesne favored to win men's college basketball matchup [1/24/2026]

Loyola Chicago will face the favored Duquesne in men's college basketball action at Joseph J. Gentile Arena on Saturday, beginning at 2:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects Duquesne as the most likely winner of the Duquesne vs. Loyola Chicago game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Duquesne vs. Loyola Chicago prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball matchup between Duquesne and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Duquesne a 68% chance of beating Loyola Chicago. Our predicted final score has Duquesne winning 76-72.

According to our model, Loyola Chicago (+5.5) has a 55% chance of covering the spread, while the over/under total of 152.5 points has a 55% chance of staying under.

Duquesne vs. Loyola Chicago odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Duquesne vs. Loyola Chicago picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Loyola Chicago +5.5 at the spread.

Duquesne vs. Loyola Chicago game-day updates and essential details

Saturday's men's college basketball matchup between Loyola Chicago and Duquesne at Joseph J. Gentile Arena is scheduled to start at 2:00 PM ET.

• Who: Duquesne vs. Loyola Chicago
• Date: Saturday, January 24, 2026
• Time: 2:00 PM ET/11:00AM PT
• Venue: Joseph J. Gentile Arena

Conclusion

We predict Duquesne, with a 68% win probability, will likely beat Loyola Chicago on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Duquesne vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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