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Duke vs. West Virginia prediction: Why Duke is favored to win women's college basketball matchup [11/14/2025]
Get Duke vs West Virginia predictions for college basketball Friday.

West Virginia and Duke will meet in the women's college basketball at Colonial Hall on Friday, with tipoff at 7:00PM ET.
Based on updated simulations, Dimers' new women's basketball model predicts Duke as the most likely winner of the Duke vs. West Virginia game.
This article offers an expanded analysis of Friday's matchup, including best bets and picks.
Duke vs. West Virginia prediction: Who will win?
Using innovative machine learning and statistical analysis, we have simulated the outcome of Friday's women's basketball game between Duke and West Virginia 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Duke an 81% chance of beating West Virginia.
According to our model, the over/under total of 131.5 points has a 65% chance of staying under.
Duke vs. West Virginia odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Duke | West Virginia |
|---|---|---|
| Spread | -5.5 (-110) | +5.5 (-110) |
| Moneyline | -235 | +215 |
| Total | o131.5 (-110) | u131.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Duke vs. West Virginia picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke -5.5 | -110 |
| Moneyline | Duke | -235 |
| Total | Under 131.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Under 131.5 total points.
Duke vs. West Virginia game-day updates and essential details
Friday's women's basketball matchup between West Virginia and Duke at Colonial Hall is scheduled to commence at 7:00PM ET.
- Who: Duke vs. West Virginia
- Date: Friday, November 14, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Colonial Hall
Conclusion
We predict Duke, with an 81% win probability, will likely beat West Virginia on Friday.
AI and automation have enhanced this article to quickly deliver accurate Duke vs. West Virginia insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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