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Duke vs. Virginia Tech prediction: Duke favored to win women's college basketball matchup [12/7/2025]
Get Duke vs Virginia Tech predictions for college basketball Sunday.

Virginia Tech and Duke will meet in the women's college basketball at Cassell Coliseum on Sunday, starting at 2:00PM ET.
Based on the latest simulations, Dimers' new women's basketball model predicts Duke as the most likely winner of the Duke vs. Virginia Tech game.
This article offers a closer look at Sunday's matchup, including best bets and picks.
Duke vs. Virginia Tech prediction: Who will win?
Using innovative machine learning and data, we have simulated the result of Sunday's women's basketball game between Duke and Virginia Tech 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model gives Duke a 91% chance of defeating Virginia Tech.
According to our model, the over/under total of 133.5 points has a 58% chance of staying under.
Duke vs. Virginia Tech odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Duke | Virginia Tech |
|---|---|---|
| Spread | -5.5 (-110) | +5.5 (-110) |
| Moneyline | -218 | +210 |
| Total | o133.5 (-110) | u133.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Duke vs. Virginia Tech picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke -5.5 | -110 |
| Moneyline | Duke | -218 |
| Total | Under 133.5 | -110 |
According to our best women's college basketball bets, the top play to make on this game is Duke -5.5 at the spread.
Duke vs. Virginia Tech game-day updates and essential details
Sunday's women's basketball matchup between Virginia Tech and Duke at Cassell Coliseum is scheduled to begin at 2:00PM ET.
- Who: Duke vs. Virginia Tech
- Date: Sunday, December 7, 2025
- Time: 2:00PM ET/11:00AM PT
- Venue: Cassell Coliseum
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Conclusion
We predict Duke, with a 91% win probability, will likely beat Virginia Tech on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Duke vs. Virginia Tech insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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