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Duke vs. Pittsburgh prediction: Why Duke is favored to win men's college basketball matchup [2/10/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Duke vs Pittsburgh predictions for college basketball Tuesday.
Pittsburgh and Duke will meet in men's college basketball action at Petersen Events Center on Tuesday, starting at 9:00 PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts Duke as the most likely winner of the Duke vs. Pittsburgh game.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Duke vs. Pittsburgh prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the result of Tuesday's NCAA basketball matchup between Duke and Pittsburgh 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Duke a 93% chance of beating Pittsburgh. Our predicted final score has Duke winning 76-60.
According to our model, Pittsburgh (+17.5) has a 54% chance of covering the spread, while the over/under total of 136.5 points has an equal 50-50 chance of hitting.
Duke vs. Pittsburgh odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Duke | Pittsburgh |
|---|---|---|
| Spread | -17.5 (-114) | +17.5 (-105) |
| Moneyline | -2800 | +1300 |
| Total | o136.5 (-108) | u136.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Duke vs. Pittsburgh picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pittsburgh +17.5 | -105 |
| Moneyline | Pittsburgh | +1300 |
| Total | Over 136.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is Pittsburgh +17.5 at the spread.
Duke vs. Pittsburgh game-day updates and essential details
Tuesday's men's college basketball game between Pittsburgh and Duke at Petersen Events Center is scheduled to start at 9:00 PM ET.
- Who: Duke vs. Pittsburgh
- Date: Tuesday, February 10, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Petersen Events Center
Conclusion
We predict Duke, with a 93% win probability, will likely beat Pittsburgh on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Duke vs. Pittsburgh insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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