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Duke vs. Liberty prediction: Duke favored to win women's college basketball matchup [11/16/2025]

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Written by Ryan Leaver

Get Duke vs Liberty predictions for college basketball Sunday.

Duke-Liberty Predictions and Game Preview.
Duke vs. Liberty women's college basketball prediction for Sunday, November 16, 2025.

Women's college basketball action continues on Sunday at 2:00PM ET as the favored Duke locks horns with Liberty at Liberty Arena.

Based on the latest simulation results, Dimers' new women's basketball model predicts Duke as the most likely winner of the Duke vs. Liberty game.

This article offers a closer look at Sunday's matchup, including best bets and picks.

Duke vs. Liberty prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Sunday's women's basketball matchup between Duke and Liberty 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model currently gives Duke a 98% chance of beating Liberty.

According to our model, the 123.5-point over/under has a 53% chance of staying under.

 

Duke vs. Liberty odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Duke Liberty
Spread -21.5 (-118) +21.5 (-104)
Moneyline -4000 +1600
Total o123.5 (-110) u123.5 (-110)

All odds are correct at the time of publication and are subject to change.

Duke vs. Liberty picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Liberty +21.5 -104
Moneyline Duke -4000
Total Under 123.5 -110

According to our women's college basketball best bets, the top play to make on this game is Liberty +21.5 at the spread.

 

Duke vs. Liberty game-day updates and essential details

Sunday's women's basketball matchup between Liberty and Duke at Liberty Arena is scheduled to commence at 2:00PM ET.

  • Who: Duke vs. Liberty
  • Date: Sunday, November 16, 2025
  • Time: 2:00PM ET/11:00AM PT
  • Venue: Liberty Arena

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Conclusion

We predict Duke, with a 98% win probability, will likely beat Liberty on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Duke vs. Liberty insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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