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Tigers vs. Guardians Prediction: Detroit Predicted to Win Saturday's MLB Matchup [7/5/2025]

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Written by Jason Bevilacqua

Our expert prediction for Saturday's Detroit Tigers vs Cleveland Guardians matchup.

Detroit Tigers-Cleveland Guardians Predictions and Game Preview.
Progressive Field sets the stage for the MLB matchup between the Detroit Tigers and Cleveland Guardians this Saturday.

The Cleveland Guardians will face the Detroit Tigers in MLB action at Progressive Field on Saturday, commencing at 7:15PM ET.

Logan Allen (5-6, 4.27 ERA) will start for the Guardians, up against Casey Mize (8-2, 2.86 ERA) for the Tigers.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Tigers as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Tigers vs. Guardians predictions page.

Guardians vs. Tigers Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Saturday's MLB matchup between the Tigers and Guardians 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Tigers a 51% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 61% chance of covering the run line, while the over/under total of 9 runs has a 54% chance of staying under.

 

Tigers vs. Guardians Odds [7/5/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Tigers Guardians
Run Line -1.5 (+125) +1.5 (-142)
Moneyline -136 +120
Total o9 (-101) u9 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Tigers vs. Guardians Picks and Best Bets

Our model's strongest edge in today's Tigers vs. Guardians matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Tigers vs. Guardians Game-Day Updates and Essential Details

Saturday's MLB game between the Guardians and Tigers at Progressive Field is scheduled to begin at 7:15PM ET.

Dimers.com's comprehensive preview of Saturday's Tigers vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Tigers vs. Guardians picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Tigers, with a 51% win probability, will likely beat the Guardians on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most up-to-date predictions for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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