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Pistons vs. Clippers prediction: Detroit favored to win Sunday's NBA matchup [12/28/2025]

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Written by Jason Bevilacqua

Get Detroit Pistons vs Los Angeles Clippers predictions for NBA Sunday.

Detroit Pistons-Los Angeles Clippers Predictions and Game Preview.
Detroit Pistons vs. Los Angeles Clippers NBA prediction for Sunday, December 28, 2025.

The Los Angeles Clippers and Detroit Pistons will meet in NBA action at Intuit Dome on Sunday, with tipoff at 9:00 PM ET.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Pistons vs. Clippers game.

This prediction follows the latest NBA Injury Report, which suggests the Clippers lineup will feature players like Kawhi Leonard, James Harden and Brook Lopez, while the Pistons will look to Cade Cunningham, Jalen Duren and Tobias Harris.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pistons vs. Clippers prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Sunday's NBA game between the Pistons and Clippers 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Pistons a 63% chance of defeating the Clippers. Our predicted final score has the Pistons winning 114-110.

According to our model, the Pistons (-4.5) have a 52% chance of covering the spread, while the 224.5-point over/under has a 51% chance of going over.

 

Pistons vs. Clippers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Pistons Clippers
Spread -4.5 (-105) +4.5 (-115)
Moneyline -155 +140
Total o224.5 (-106) u224.5 (-110)

All odds are correct at the time of publication and are subject to change.

Pistons vs. Clippers picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Pistons -4.5 -105
Moneyline Pistons -155
Total Over 224.5 -106

According to our best NBA bets for Sunday, the top play to make on this game is Pistons to win.

 

Pistons vs. Clippers player props

NBA prop bets are an exciting way to wager on Sunday's Pistons vs. Clippers matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Intuit Dome.

Cade Cunningham is expected to lead the Pistons with 28 points, 6 rebounds and 9 assists, while Kawhi Leonard is projected to have 27 points, 7 rebounds and 4 assists for the Clippers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Pistons prediction

Our model's projected player stats for the Pistons are:

Player PTS REB AST 3PM DFS
Cade Cunningham 28 6 9 2 57
Jalen Duren 16 10 3 0 37
Tobias Harris 13 4 2 1 25
Duncan Robinson 11 2 2 3 21
Ausar Thompson 11 5 2 0 26

Clippers prediction

Projected points, rebounds, assists and three-pointers made for the Clippers:

Player PTS REB AST 3PM DFS
Kawhi Leonard 27 7 4 2 48
James Harden 25 5 8 3 51
Brook Lopez 12 5 2 3 28
Kris Dunn 9 3 3 2 23
Kobe Sanders 8 2 1 1 17

Pistons vs. Clippers game-day updates and essential details

Sunday's matchup between the Clippers and Pistons at Intuit Dome is scheduled to start at 9:00 PM ET.

Conclusion

We predict the Pistons, with a 63% win probability, will likely beat the Clippers on Sunday, with Cade Cunningham projected for a game-high 57 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Clippers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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