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Pistons vs. Clippers prediction: Detroit favored to win Sunday's NBA matchup [12/28/2025]

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Written by Jason Bevilacqua

Get Detroit Pistons vs Los Angeles Clippers predictions for NBA Sunday.

Detroit Pistons-Los Angeles Clippers Predictions and Game Preview.
Detroit Pistons vs. Los Angeles Clippers NBA prediction for Sunday, December 28, 2025.

The Los Angeles Clippers will square off with the Detroit Pistons in NBA action at Intuit Dome on Sunday, starting at 9:00 PM ET.

Based on updated simulations and today’s injury updates, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Pistons vs. Clippers game.

This prediction follows the latest NBA Injury Report, which suggests the Clippers lineup will feature players like Kawhi Leonard, James Harden and John Collins, while the Pistons will rely on Cade Cunningham, Jalen Duren and Tobias Harris.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pistons vs. Clippers prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's NBA matchup between the Pistons and Clippers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Pistons a 63% chance of beating the Clippers. Our predicted final score has the Pistons winning 113-110.

According to our model, the Pistons (-3.5) have a 51% chance of covering the spread, while the 224.5-point over/under has an equal 50-50 chance of hitting.

 

Pistons vs. Clippers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Pistons Clippers
Spread -3.5 (-105) +3.5 (-115)
Moneyline -154 +136
Total o224.5 (-108) u224.5 (-110)

All odds are correct at the time of publication and are subject to change.

Pistons vs. Clippers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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