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Pistons vs. Celtics prediction: Boston favored to win Monday's NBA game [12/15/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Detroit Pistons vs Boston Celtics predictions for NBA Monday.
The Boston Celtics and Detroit Pistons are scheduled to meet in NBA action at TD Garden on Monday, with tipoff at 7:00PM ET.
Based on updated simulation results and today’s injury news, Dimers' advanced NBA model predicts the Celtics as the most likely winner of the Pistons vs. Celtics game.
This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature players like Jaylen Brown, Derrick White and Payton Pritchard, while the Pistons will look to Cade Cunningham, Jalen Duren and Tobias Harris.
This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pistons vs. Celtics prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the outcome of Monday's NBA matchup between the Pistons and Celtics 10,000 times as part of our NBA predictions coverage.
Our famous predictive model currently gives the Celtics a 58% chance of defeating the Pistons. Our predicted final score has the Celtics winning 115-113.
According to our model, the Celtics (-2.5) have a 53% chance of covering the spread, while the over/under total of 229.5 points has a 51% chance of staying under.
Pistons vs. Celtics odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Pistons | Celtics |
|---|---|---|
| Spread | +2.5 (-115) | -2.5 (-105) |
| Moneyline | +106 | -122 |
| Total | o229.5 (-106) | u229.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Pistons vs. Celtics picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Celtics -2.5 | -105 |
| Moneyline | Celtics | -122 |
| Total | Under 229.5 | -110 |
According to our best NBA bets for Monday, the top play to make on this game is Celtics -2.5 at the spread.
Pistons vs. Celtics player props
Betting on Detroit vs. Boston NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at TD Garden.
Cade Cunningham is expected to lead the Pistons with 26 points, 6 rebounds and 8 assists, while Jaylen Brown is projected to have 27 points, 6 rebounds and 5 assists for the Celtics.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Pistons prediction
Our model's projected player stats for the Pistons are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Cade Cunningham | 26 | 6 | 8 | 2 | 53 |
| Jalen Duren | 16 | 11 | 2 | 0 | 38 |
| Tobias Harris | 14 | 5 | 2 | 1 | 26 |
| Duncan Robinson | 12 | 3 | 2 | 3 | 22 |
| Ausar Thompson | 12 | 6 | 3 | 0 | 27 |
Celtics prediction
Projected points, rebounds, assists and three-pointers made for the Celtics:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaylen Brown | 27 | 6 | 5 | 2 | 48 |
| Derrick White | 18 | 4 | 5 | 3 | 38 |
| P. Pritchard | 17 | 4 | 4 | 3 | 32 |
| Anfernee Simons | 13 | 2 | 3 | 2 | 22 |
| Neemias Queta | 10 | 9 | 2 | 0 | 29 |
Pistons vs. Celtics game-day updates and essential details
Monday's matchup between the Celtics and Pistons at TD Garden is scheduled to start at 7:00PM ET.
- Who: Detroit Pistons vs. Boston Celtics
- Date: Monday, December 15, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: TD Garden
Conclusion
We predict the Celtics, with a 58% win probability, will likely beat the Pistons on Monday, with Cade Cunningham projected for a game-high 53 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Celtics insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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