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Detroit Mercy vs. DePaul prediction: DePaul favored to win men's college basketball matchup [11/23/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Detroit Mercy vs DePaul predictions for college basketball Sunday.
DePaul will face Detroit Mercy in men's college basketball action at Wintrust Arena on Sunday, beginning at 6:00PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model projects DePaul as the most likely winner of the Detroit Mercy vs. DePaul game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Detroit Mercy vs. DePaul prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Sunday's NCAA basketball game between Detroit Mercy and DePaul 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives DePaul a 96% chance of beating Detroit Mercy. Our predicted final score has DePaul winning 85-65.
According to our model, the bookmakers have got it right, and Detroit Mercy and DePaul each have a 50% chance of covering the spread, while the over/under total of 152.5 points has a 53% chance of staying under.
Detroit Mercy vs. DePaul odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Detroit Mercy | DePaul |
|---|---|---|
| Spread | +20.5 (-114) | -20.5 (-105) |
| Moneyline | +1600 | -2800 |
| Total | o152.5 (-110) | u152.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Detroit Mercy vs. DePaul picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul -20.5 | -105 |
| Moneyline | DePaul | -2800 |
| Total | Under 152.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 152.5 total points.
Detroit Mercy vs. DePaul game-day updates and essential details
Sunday's men's college basketball matchup between DePaul and Detroit Mercy at Wintrust Arena is scheduled to commence at 6:00PM ET.
- Who: Detroit Mercy vs. DePaul
- Date: Sunday, November 23, 2025
- Time: 6:00PM ET/3:00PM PT
- Venue: Wintrust Arena
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Conclusion
We predict DePaul, with a 96% win probability, will likely beat Detroit Mercy on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Detroit Mercy vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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