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Lions vs. Vikings prediction: Why Detroit is favored to win in NFL Week 17 [2025]

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Written by Jason Bevilacqua

Get Detroit Lions vs Minnesota Vikings predictions for NFL Thursday.

Detroit Lions-Minnesota Vikings Predictions and Game Preview.
Detroit Lions vs. Minnesota Vikings NFL prediction for Thursday, December 25, 2025.

NFL Week 17 action continues on Christmas Day at 4:30 PM ET as the favored Detroit Lions take on the Minnesota Vikings at U.S. Bank Stadium.

Based on the latest simulation results, Dimers' proven NFL model predicts the Lions as the most likely winner of the Lions vs. Vikings game.

This article offers further insights into Thursday's matchup, including projected touchdown scorers, best bets and player prop picks.

Lions vs. Vikings prediction: Who will win and cover?

Since our Lions-Vikings predictions earlier in the week, we have simulated the outcome of Thursday's NFL matchup between the Lions and Vikings 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Lions a 77% chance of beating the Vikings in Week 17 of the NFL season. Our predicted final score has the Lions winning 25-18.

According to our model, the bookmakers have got it right, and the Lions and Vikings each have a 50% chance of covering the spread, while the over/under total of 43 points has a 52% chance of going over.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 17 straight up picks.

Lions vs. Vikings odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Lions Vikings
Spread -7.5 (-102) +7.5 (-115)
Moneyline -360 +300
Total o43 (-110) u43 (-110)

All odds are correct at the time of publication and are subject to change.

Lions vs. Vikings picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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