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Lions vs. Rams prediction: Rams favored to win in NFL Week 15 [2025]

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Written by Jason Bevilacqua

Get Detroit Lions vs Los Angeles Rams predictions for NFL Sunday.

Detroit Lions-Los Angeles Rams Predictions and Game Preview.
Detroit Lions vs. Los Angeles Rams NFL prediction for Sunday, December 14, 2025.

NFL Week 15 action continues on Sunday at 4:25PM ET as the Detroit Lions take on the favored Los Angeles Rams at SoFi Stadium.

Based on updated simulation results, Dimers' proven NFL model predicts the Rams as the most likely winner of the Lions vs. Rams game.

This article offers an expanded analysis of this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Lions vs. Rams prediction: Who will win and cover?

Since our Lions-Rams predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Lions and Rams 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Rams a 68% chance of beating the Lions in Week 15 of the NFL season. Our predicted final score has the Rams winning 30-24.

According to our model, the Lions (+6) have a 51% chance of covering the spread, while the 54.5-point over/under has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 15 straight up picks.

Lions vs. Rams odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Lions Rams
Spread +6 (-110) -6 (-108)
Moneyline +215 -245
Total o54.5 (-115) u54.5 (-102)

All odds are correct at the time of publication and are subject to change.

Lions vs. Rams picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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