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DePaul vs. Xavier prediction: Xavier favored to win men's college basketball matchup [1/31/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get DePaul vs Xavier predictions for college basketball Saturday.
Xavier will face DePaul in men's college basketball action at Cintas Center on Saturday, commencing at 1:00 PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model projects Xavier as the most likely winner of the DePaul vs. Xavier game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
DePaul vs. Xavier prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between DePaul and Xavier 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Xavier a 65% chance of beating DePaul. Our predicted final score has Xavier winning 77-73.
According to our model, the bookmakers have got it right, and DePaul and Xavier each have a 50% chance of covering the spread, while the 150.5-point over/under also has an equal 50-50 chance of hitting.
DePaul vs. Xavier odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | DePaul | Xavier |
|---|---|---|
| Spread | +4.5 (-114) | -4.5 (-105) |
| Moneyline | +172 | -190 |
| Total | o150.5 (-110) | u150.5 (-108) |
All odds are correct at the time of publication and are subject to change.
DePaul vs. Xavier picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Xavier -4.5 | -105 |
| Moneyline | Xavier | -190 |
| Total | Under 150.5 | -108 |
According to our best men's college basketball bets, the top play to make on this game is Xavier to win.
DePaul vs. Xavier game-day updates and essential details
Saturday's men's college basketball action between Xavier and DePaul at Cintas Center is scheduled to begin at 1:00 PM ET.
- Who: DePaul vs. Xavier
- Date: Saturday, January 31, 2026
- Time: 1:00 PM ET/10:00AM PT
- Venue: Cintas Center
Conclusion
We predict Xavier, with a 65% win probability, will likely beat DePaul on Saturday.
AI and automation have enhanced this article to quickly deliver accurate DePaul vs. Xavier insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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