DePaul vs. Creighton Prediction: Creighton Predicted to Win College Basketball Matchup [3/13/2025]

Creighton will take on DePaul in college basketball action at Madison Square Garden on Thursday, starting at 7:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Creighton as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Using the latest data, our experts simulated Thursday's DePaul-Creighton game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast Creighton with a win probability of 89% and DePaul with 11%."

For expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive DePaul vs. Creighton predictions page.

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DePaul vs. Creighton Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Thursday's NCAA basketball game between DePaul and Creighton 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model gives Creighton an 89% chance of defeating DePaul. Our predicted final score has Creighton winning 79-66.

According to our model, Creighton (-12.5) has a 54% chance of covering the spread, while the over/under total of 142.5 points has a 55% chance of going over.

DePaul vs. Creighton Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

Bet Type	DePaul	Creighton
Spread	+12.5 (-105)	-12.5 (-110)
Moneyline	+675	-880
Total	o142.5 (-110)	u142.5 (-108)

All odds are correct at the time of publication and are subject to change.

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DePaul vs. Creighton Picks and Best Bets

Our model's strongest edge in today's DePaul vs. Creighton matchup is on the spread.

Our expert predictions, matched against the latest odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

DePaul vs. Creighton Game-Day Updates and Essential Details

Thursday's college basketball game between Creighton and DePaul at Madison Square Garden is scheduled to start at 7:00PM ET.

• Who: DePaul vs. Creighton
• Date: Thursday, March 13, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Madison Square Garden

Dimers.com's full preview of Thursday's DePaul vs. Creighton matchup includes our prediction, picks and the latest betting odds.

Before making any DePaul vs. Creighton picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

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Conclusion

We predict Creighton, with an 89% win probability, will likely beat DePaul on Thursday.

AI and automation have enhanced this article to quickly deliver accurate DePaul vs. Creighton insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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