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DePaul vs. Butler prediction: Butler favored to win men's college basketball matchup [1/20/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get DePaul vs Butler predictions for college basketball Tuesday.
Butler will take on DePaul in men's college basketball action at Hinkle Fieldhouse on Tuesday, beginning at 7:30 PM ET.
Based on updated simulation results, Dimers' proven college basketball model projects Butler as the most likely winner of the DePaul vs. Butler game.
This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
DePaul vs. Butler prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball game between DePaul and Butler 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Butler a 74% chance of beating DePaul. Our predicted final score has Butler winning 79-72.
According to our model, DePaul (+7.5) has a 54% chance of covering the spread, while the 148.5-point over/under has a 55% chance of going over.
DePaul vs. Butler odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | DePaul | Butler |
|---|---|---|
| Spread | +7.5 (-115) | -7.5 (-105) |
| Moneyline | +260 | -310 |
| Total | o148.5 (-105) | u148.5 (-105) |
All odds are correct at the time of publication and are subject to change.
DePaul vs. Butler picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul +7.5 | -115 |
| Moneyline | DePaul | +260 |
| Total | Over 148.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 148.5 total points.
DePaul vs. Butler game-day updates and essential details
Tuesday's men's college basketball game between Butler and DePaul at Hinkle Fieldhouse is scheduled to commence at 7:30 PM ET.
- Who: DePaul vs. Butler
- Date: Tuesday, January 20, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Hinkle Fieldhouse
Conclusion
We predict Butler, with a 74% win probability, will likely beat DePaul on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate DePaul vs. Butler insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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