Denver vs. South Dakota prediction: Denver favored to win men's college basketball matchup [1/10/2026]

South Dakota will square off with Denver in men's college basketball action at Sanford Coyote Sports Center on Saturday, commencing at 2:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Denver as the most likely winner of the Denver vs. South Dakota game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Denver vs. South Dakota prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Denver and South Dakota 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Denver a 55% chance of beating South Dakota. Our predicted final score has Denver winning 82-80.

According to our model, the bookies have got it right, and Denver and South Dakota each have a 50% chance of covering the spread, while the over/under total of 170.5 points has a 54% chance of staying under.

Denver vs. South Dakota odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Denver vs. South Dakota picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: