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Dayton vs. La Salle prediction: Dayton favored to win men's college basketball matchup [1/21/2026]

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Written by Mac Douglass

Get Dayton vs La Salle predictions for college basketball Wednesday.

Dayton-La Salle Predictions and Game Preview.
Dayton vs. La Salle men's college basketball prediction for Wednesday, January 21, 2026.

La Salle will take on the favored Dayton in men's college basketball action at John Glaser Arena on Wednesday, beginning at 6:30 PM ET.

Based on updated simulations, Dimers' proven college basketball model projects Dayton as the most likely winner of the Dayton vs. La Salle game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Dayton vs. La Salle prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Wednesday's NCAA basketball matchup between Dayton and La Salle 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Dayton an 87% chance of beating La Salle. Our predicted final score has Dayton winning 75-64.

According to our model, Dayton (-10.5) has a 54% chance of covering the spread, while the over/under total of 137.5 points has a 54% chance of going over.

 

Dayton vs. La Salle odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Dayton La Salle
Spread -10.5 (-102) +10.5 (-115)
Moneyline -580 +450
Total o137.5 (-110) u137.5 (-105)

All odds are correct at the time of publication and are subject to change.

Dayton vs. La Salle picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Dayton -10.5 -102
Moneyline Dayton -580
Total Over 137.5 -110

According to our men's college basketball best bets, the top play to make on this game is Dayton -10.5 at the spread.

 

Dayton vs. La Salle game-day updates and essential details

Wednesday's men's college basketball matchup between La Salle and Dayton at John Glaser Arena is scheduled to commence at 6:30 PM ET.

  • Who: Dayton vs. La Salle
  • Date: Wednesday, January 21, 2026
  • Time: 6:30 PM ET/3:30PM PT
  • Venue: John Glaser Arena

Conclusion

We predict Dayton, with an 87% win probability, will likely beat La Salle on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Dayton vs. La Salle insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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