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Creighton vs. DePaul prediction: Creighton favored to win men's college basketball matchup [2/11/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Creighton vs DePaul predictions for college basketball Wednesday.
DePaul and Creighton are scheduled to meet in men's college basketball action at Wintrust Arena on Wednesday, with tipoff at 9:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model gives Creighton a slight edge with a 53% win probability over DePaul.
This article offers an expanded analysis of Wednesday's Creighton vs. DePaul matchup, including an expanded look at the predicted score, best bets and picks.
Creighton vs. DePaul prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Creighton and DePaul 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Creighton a 53% chance of defeating DePaul. Our predicted final score has Creighton winning 71-70.
According to our model, DePaul (+1.5) has a 53% chance of covering the spread, while the 141.5-point over/under has a 52% chance of going over.
Creighton vs. DePaul odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Creighton | DePaul |
|---|---|---|
| Spread | -1.5 (+100) | +1.5 (-115) |
| Moneyline | -115 | +104 |
| Total | o141.5 (-110) | u141.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Creighton vs. DePaul picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul +1.5 | -115 |
| Moneyline | Creighton | -115 |
| Total | Over 141.5 | -110 |
According to our best men's college basketball bets, the top play to make on this game is Over 141.5 total points.
Creighton vs. DePaul game-day updates and essential details
Wednesday's men's college basketball action between DePaul and Creighton at Wintrust Arena is scheduled to begin at 9:00 PM ET.
- Who: Creighton vs. DePaul
- Date: Wednesday, February 11, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Wintrust Arena
Conclusion
We predict Creighton, with a 53% win probability, will likely beat DePaul on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Creighton vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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