Coppin State vs. La Salle prediction: La Salle favored to win men's college basketball matchup [11/5/2025]

Men's college basketball action continues on Wednesday at 6:30PM ET as Coppin State looks to defy the odds against La Salle in men's college basketball action at John Glaser Arena.

Based on updated simulation results, Dimers' proven college basketball model projects La Salle as the most likely winner of the Coppin State vs. La Salle game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Coppin State vs. La Salle prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Coppin State and La Salle 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives La Salle a 94% chance of beating Coppin State. Our predicted final score has La Salle winning 78-61.

According to our model, Coppin State (+17.5) has a 52% chance of covering the spread, while the over/under total of 139.5 points has an equal 50-50 chance of hitting.

Coppin State vs. La Salle odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Coppin State vs. La Salle picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Coppin State +17.5 at the spread.

Coppin State vs. La Salle game-day updates and essential details

Wednesday's men's college basketball action between La Salle and Coppin State at John Glaser Arena is scheduled to start at 6:30PM ET.

• Who: Coppin State vs. La Salle
• Date: Wednesday, November 5, 2025
• Time: 6:30PM ET/3:30PM PT
• Venue: John Glaser Arena

Conclusion

We predict La Salle, with a 94% win probability, will likely beat Coppin State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Coppin State vs. La Salle insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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