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Colorado State vs. Loyola Chicago prediction: Colorado State favored to win men's college basketball matchup [11/16/2025]

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Written by Jason Bevilacqua

Get Colorado State vs Loyola Chicago predictions for college basketball Sunday.

Colorado State-Loyola Chicago Predictions and Game Preview.
Colorado State vs. Loyola Chicago men's college basketball prediction for Sunday, November 16, 2025.

Loyola Chicago will take on Colorado State in men's college basketball action at Joseph J. Gentile Arena on Sunday, commencing at 5:00PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts Colorado State as the most likely winner of the Colorado State vs. Loyola Chicago game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Colorado State vs. Loyola Chicago prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Sunday's NCAA basketball matchup between Colorado State and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Colorado State a 60% chance of defeating Loyola Chicago. Our predicted final score has Colorado State winning 76-73.

According to our model, Loyola Chicago (+3.5) has a 56% chance of covering the spread, while the over/under total of 151.5 points has a 53% chance of staying under.

 

Colorado State vs. Loyola Chicago odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

Bet Type Colorado State Loyola Chicago
Spread -3.5 (-115) +3.5 (-102)
Moneyline -190 +164
Total o151.5 (-110) u151.5 (-105)

All odds are correct at the time of publication and are subject to change.

Colorado State vs. Loyola Chicago picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Loyola Chicago +3.5 -102
Moneyline Loyola Chicago +164
Total Under 151.5 -105

According to our men's college basketball best bets, the top play to make on this game is Loyola Chicago +3.5 at the spread.

 

Colorado State vs. Loyola Chicago game-day updates and essential details

Sunday's men's college basketball matchup between Loyola Chicago and Colorado State at Joseph J. Gentile Arena is scheduled to commence at 5:00PM ET.

  • Who: Colorado State vs. Loyola Chicago
  • Date: Sunday, November 16, 2025
  • Time: 5:00PM ET/2:00PM PT
  • Venue: Joseph J. Gentile Arena

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Conclusion

We predict Colorado State, with a 60% win probability, will likely beat Loyola Chicago on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Colorado State vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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