Colgate vs. St. Bonaventure prediction: St. Bonaventure favored to win men's college basketball matchup [12/10/2025]

St. Bonaventure and Colgate will lock horns in men's college basketball action at Reilly Center on Wednesday, starting at 7:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts St. Bonaventure as the most likely winner of the Colgate vs. St. Bonaventure game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Colgate vs. St. Bonaventure prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Wednesday's NCAA basketball game between Colgate and St. Bonaventure 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives St. Bonaventure an 86% chance of beating Colgate. Our predicted final score has St. Bonaventure winning 78-66.

According to our model, St. Bonaventure (-9.5) has a 54% chance of covering the spread, while the over/under total of 143.5 points has a 53% chance of going over.

Colgate vs. St. Bonaventure odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Colgate vs. St. Bonaventure picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: