Cavaliers vs. Heat prediction: Why Miami is favored to win Wednesday's NBA matchup [11/12/2025]

The Miami Heat and Cleveland Cavaliers are scheduled to meet in NBA action at Kaseya Center on Wednesday, starting at 7:30PM ET.

Based on updated simulations and today’s injury news, Dimers' advanced NBA model predicts the Heat as the most likely winner of the Cavaliers vs. Heat game.

This prediction follows the latest NBA Injury Report, which suggests the Heat lineup will feature stars like Norman Powell, Andrew Wiggins and Jaime Jaquez, while the Cavaliers will rely on De'Andre Hunter, Jarrett Allen and Sam Merrill.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Cavs vs. Heat prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NBA matchup between the Cavaliers and Heat 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Heat a 67% chance of defeating the Cavaliers. Our predicted final score has the Heat winning 121-116.

According to our model, the bookmakers have got it right, and the Cavaliers and Heat each have a 50% chance of covering the spread, while the 238.5-point over/under has a 53% chance of staying under.

Cavaliers vs. Heat odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Cavaliers	Heat
Spread	+4.5 (-105)	-4.5 (-115)
Moneyline	+168	-192
Total	o238.5 (-115)	u238.5 (-105)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. Heat picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Cavaliers +4.5	-105
Moneyline	Heat	-192
Total	Under 238.5	-105

According to our best NBA bets for Wednesday, the top play to make on this game is Heat to win.

Cavaliers vs. Heat player props

NBA player props are a great way to wager on the Cleveland vs. Miami matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Kaseya Center.

De'Andre Hunter is expected to lead the Cavaliers with 22 points, 5 rebounds and 3 assists, while Norman Powell is projected to have 20 points, 3 rebounds and 2 assists for the Heat.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Cavaliers prediction

Our model's projected player stats for the Cavaliers are:

Player	PTS	REB	AST	3PM	DFS
De'Andre Hunter	22	5	3	3	37
Jarrett Allen	15	10	2	0	36
Sam Merrill	14	4	3	4	27
Lonzo Ball	9	4	5	2	28
Tyrese Proctor	9	2	2	2	19

Heat prediction

Projected points, rebounds, assists and three-pointers made for the Heat:

Player	PTS	REB	AST	3PM	DFS
Norman Powell	20	3	2	2	32
Andrew Wiggins	20	5	3	2	36
Jaime Jaquez	16	7	4	1	35
Nikola Jovic	12	5	4	2	28
Kel'el Ware	11	10	1	1	30

Cavs vs. Heat game-day updates and essential details

Wednesday's matchup between the Heat and Cavaliers at Kaseya Center is scheduled to commence at 7:30PM ET.

• Who: Cleveland Cavaliers vs. Miami Heat
• Date: Wednesday, November 12, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Kaseya Center

Conclusion

We predict the Heat, with a 67% win probability, will likely beat the Cavaliers on Wednesday, with De'Andre Hunter projected for 37 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. Heat insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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