Reds vs. Astros Prediction: Houston Predicted to Win Friday's MLB Matchup [5/9/2025]

The Houston Astros and Cincinnati Reds will lock horns in MLB action at Daikin Park on Friday, starting at 8:10PM ET.

The Astros will start Hunter Brown (5-1, 1.67 ERA), up against Nick Martinez (1-3, 4.19 ERA) for the Reds.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Cincinnati-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Astros' chance of winning is 64%, while the Reds' is 36%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Reds vs. Astros predictions page.

Astros vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Friday's MLB matchup between the Reds and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 64% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 56% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of staying under.

Reds vs. Astros Odds [5/9/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Reds	Astros
Run Line	+1.5 (-130)	-1.5 (+114)
Moneyline	+165	-185
Total	o7.5 (+100)	u7.5 (-118)

All odds are correct at the time of publication and are subject to change.

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Reds vs. Astros Picks and Best Bets

Our model's strongest edge in today's Reds vs. Astros matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Reds vs. Astros Game-Day Updates and Essential Details

Friday's MLB matchup between the Astros and Reds at Daikin Park is scheduled to commence at 8:10PM ET.

• Who: Cincinnati Reds vs. Houston Astros
• Date: Friday, May 9, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Friday's Reds vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 64% win probability, will likely beat the Reds on Friday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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