May 31, 2026
Blue Jays vs. Orioles prediction: Baltimore favored to win Sunday's MLB matchup [5/31/2026]
Read Article Cubs vs. Cardinals prediction: Cubs favored to win Sunday's MLB matchup [5/31/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Chicago Cubs vs St. Louis Cardinals predictions for MLB Sunday.
The St. Louis Cardinals will face the Chicago Cubs, in what is expected to be a tight MLB game, at Busch Stadium on Sunday, beginning at 7:20 PM ET.
The Cardinals will have Matthew Liberatore (2-3, 4.76 ERA) as their starting pitcher, up against Jordan Wicks (0-1, 16.62 ERA) for the Cubs.
Based on updated simulation results, Dimers' advanced MLB model gives the Cubs a slight edge with a 54% win probability over the Cardinals.
This article offers an expanded analysis of Sunday's Cubs vs. Cardinals matchup, including best bets and picks.
Cubs vs. Cardinals prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Sunday's MLB game between the Cubs and Cardinals, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Cubs a 54% chance of beating the Cardinals.
According to our model, the Cardinals (+1.5) have a 58% chance of covering the run line, while the 8.5-run over/under has a 53% chance of going over.
Cubs vs. Cardinals odds [5/31/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Cubs | Cardinals |
|---|---|---|
| Run Line | -1.5 (+146) | +1.5 (-170) |
| Moneyline | -112 | -104 |
| Total | o8.5 (-125) | u8.5 (+105) |
All odds are correct at the time of publication and are subject to change.
Cubs vs. Cardinals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs -1.5 | +146 |
| Moneyline | Cubs | -112 |
| Total | Under 8.5 | +105 |
According to our best MLB bets, the top play to make on this game is Cubs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cubs vs. Cardinals game-day updates and essential details
Sunday's MLB matchup between the Cardinals and Cubs at Busch Stadium is scheduled to begin at 7:20 PM ET.
- Who: Chicago Cubs vs. St. Louis Cardinals
- Date: Sunday, May 31, 2026
- Time: 7:20 PM ET/4:20PM PT
- Venue: Busch Stadium
Conclusion
We predict the Cubs, with a 54% win probability, will likely beat the Cardinals in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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