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Cubs vs. Reds Prediction: Cubs Predicted to Win Sunday's MLB Matchup [5/25/2025]
Our expert prediction for Sunday's Chicago Cubs vs Cincinnati Reds matchup.

The Cincinnati Reds and Chicago Cubs will lock horns in MLB action at Great American Ball Park on Sunday, starting at 1:40PM ET.
Nick Lodolo (4-4, 3.22 ERA) will start on the mound for the Reds, up against Ben Brown (3-3, 5.44 ERA) for the Cubs.
Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's CHI Cubs-Cincinnati game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows the Cubs with a win probability of 56%, while the Reds have 44%."
For further insights into Sunday's matchup, including best bets and picks, visit our interactive Cubs vs. Reds predictions page.
Reds vs. Cubs Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Sunday's MLB matchup between the Cubs and Reds 10,000 times as part of our MLB predictions coverage.
Our leading predictive model gives the Cubs a 56% chance of beating the Reds.
According to our model, the Reds (+1.5) have a 58% chance of covering the run line, while the 9-run over/under has a 56% chance of staying under.
Cubs vs. Reds Odds [5/25/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Cubs | Reds |
---|---|---|
Run Line | -1.5 (+125) | +1.5 (-142) |
Moneyline | -125 | +114 |
Total | o9 (-102) | u9 (-115) |
All odds are correct at the time of publication and are subject to change.
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Cubs vs. Reds Picks and Best Bets
Our model's strongest edge in today's Cubs vs. Reds matchup is on the run line.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets
Calling Our Shot produces daily MLB betting content, including the free picks featured below.
Cubs vs. Reds Game-Day Updates and Essential Details
Sunday's MLB action between the Reds and Cubs at Great American Ball Park is scheduled to start at 1:40PM ET.
- Who: Chicago Cubs vs. Cincinnati Reds
- Date: Sunday, May 25, 2025
- Time: 1:40PM ET/10:40AM PT
- Venue: Great American Ball Park
Dimers.com's comprehensive preview of Sunday's Cubs vs. Reds matchup includes our prediction, picks and the latest betting odds.
Before making any CHI Cubs vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Cubs, with a 56% win probability, will likely beat the Reds on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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