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Bulls vs. Pistons prediction: Chicago favored to win Wednesday's NBA matchup [11/12/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Chicago Bulls vs Detroit Pistons predictions for NBA Wednesday.
The Detroit Pistons and Chicago Bulls will meet in NBA action at Little Caesars Arena on Wednesday, starting at 7:00PM ET.
Based on the latest simulations and today’s injury reports, Dimers' proven NBA model predicts the Bulls as the most likely winner of the Bulls vs. Pistons game.
This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature stars like Jalen Duren, Daniss Jenkins and Duncan Robinson, while the Bulls will be led by Nikola Vucevic, Matas Buzelis and Kevin Huerter.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Bulls vs. Pistons prediction: Who will win, cover the spread?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Bulls and Pistons 10,000 times as part of our NBA predictions coverage.
Our leading predictive model currently gives the Bulls a 61% chance of beating the Pistons. Our predicted final score has the Bulls winning 116-113.
According to our model, the bookies have got it right, and the Bulls and Pistons each have a 50% chance of covering the spread, while the over/under total of 229.5 points has a 51% chance of staying under.
Bulls vs. Pistons odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Bulls | Pistons |
|---|---|---|
| Spread | -2.5 (-112) | +2.5 (-105) |
| Moneyline | -148 | +130 |
| Total | o229.5 (-114) | u229.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Bulls vs. Pistons picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pistons +2.5 | -105 |
| Moneyline | Bulls | -148 |
| Total | Under 229.5 | -106 |
According to our best NBA bets for Wednesday, the top play to make on this game is Bulls to win.
Bulls vs. Pistons player props
Betting on Chicago vs. Detroit NBA player props? We have crunched the numbers to project how each team's leading players will perform at Little Caesars Arena.
Nikola Vucevic is expected to lead the Bulls with 17 points, 10 rebounds and 4 assists, while Jalen Duren is projected to have 20 points, 14 rebounds and 3 assists for the Pistons.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Bulls prediction
Our model's projected player stats for the Bulls are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Nikola Vucevic | 17 | 10 | 4 | 2 | 41 |
| Matas Buzelis | 15 | 5 | 1 | 2 | 29 |
| Kevin Huerter | 15 | 4 | 3 | 2 | 30 |
| Ayo Dosunmu | 14 | 3 | 4 | 1 | 28 |
| Tre Jones | 14 | 4 | 6 | 1 | 31 |
Pistons prediction
Projected points, rebounds, assists and three-pointers made for the Pistons:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jalen Duren | 20 | 14 | 3 | 0 | 48 |
| Daniss Jenkins | 17 | 3 | 4 | 3 | 34 |
| Duncan Robinson | 15 | 3 | 3 | 3 | 27 |
| Caris LeVert | 15 | 4 | 4 | 2 | 31 |
| Ronald Holland | 13 | 5 | 3 | 1 | 29 |
Bulls vs. Pistons game-day updates and essential details
Wednesday's game between the Pistons and Bulls at Little Caesars Arena is scheduled to begin at 7:00PM ET.
- Who: Chicago Bulls vs. Detroit Pistons
- Date: Wednesday, November 12, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Little Caesars Arena
Conclusion
We predict the Bulls, with a 61% win probability, will likely beat the Pistons on Wednesday, with Jalen Duren projected for 48 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Bulls vs. Pistons insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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