Bulls vs. Cavaliers prediction: Cleveland to win, Donovan Mitchell projected for big game in Saturday's NBA matchup [11/8/2025]

NBA action continues on Saturday at 8:00PM ET as the Chicago Bulls take on the favored Cleveland Cavaliers at Rocket Arena.

Based on updated simulation results and today’s injury news, Dimers' proven NBA model predicts the Cavaliers as the most likely winner of the Bulls vs. Cavaliers game.

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature players like Donovan Mitchell, Evan Mobley and Jarrett Allen, while the Bulls will rely on Josh Giddey, Nikola Vucevic and Matas Buzelis.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Bulls vs. Cavs prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's NBA matchup between the Bulls and Cavaliers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Cavaliers a 75% chance of defeating the Bulls. Our predicted final score has the Cavaliers winning 122-115.

According to our model, the Bulls (+8.5) have a 52% chance of covering the spread, while the 238.5-point over/under has a 52% chance of staying under.

Bulls vs. Cavaliers odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Bulls vs. Cavaliers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Saturday, the top play to make on this game is Bulls +8.5 at the spread.

Bulls vs. Cavaliers player props

NBA player props are an exciting way to wager on the Chicago vs. Cleveland game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Rocket Arena.

Josh Giddey is expected to lead the Bulls with 18 points, 8 rebounds and 8 assists, while Donovan Mitchell is projected to have 27 points, 4 rebounds and 6 assists for the Cavaliers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Bulls prediction

Our model's projected player stats for the Bulls are:

Cavaliers prediction

Projected points, rebounds, assists and three-pointers made for the Cavaliers:

Bulls vs. Cavs game-day updates and essential details

Saturday's game between the Cavaliers and Bulls at Rocket Arena is scheduled to commence at 8:00PM ET.

• Who: Chicago Bulls vs. Cleveland Cavaliers
• Date: Saturday, November 8, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Rocket Arena

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Conclusion

We predict the Cavaliers, with a 75% win probability, will likely beat the Bulls on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Bulls vs. Cavaliers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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