Chicago Bears vs. San Francisco 49ers updated prediction featuring D'Andre Swift, Christian McCaffrey [Week 17, 2025]

Dimers' latest NFL predictions are live for San Francisco 49ers vs. Chicago Bears in Week 17, with our model giving the 49ers a 61% of winning.

As Sunday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this NFC clash.

Since our early 49ers-Bears predictions, we’ve updated the win probabilities, score projections, and TD odds for D'Andre Swift, Christian McCaffrey, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Bears vs. 49ers page.

What's changed? Chicago vs. San Francisco updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Bears vs. Niners matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Bears 39%, 49ers 61%
• Predicted Final Score: Bears 24-27 49ers
• Spread: Bears (+3) 50%, 49ers (-3) 50%
• Total Points (52.5): Over 50%, Under 50%

As of December 25, 2025, these Bears-49ers calculations reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 17 highlight the top candidates to find the end zone in Bears-Niners on Sunday:

Chicago Bears

• D'Andre Swift: 39.8% probability
• DJ Moore: 36.9% probability
• Kyle Monangai: 36.3% probability

San Francisco 49ers

• Christian McCaffrey: 67.0% probability
• Jauan Jennings: 40.9% probability
• George Kittle: 40.5% probability

Bears vs. Niners latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Bears +3 (-105), 49ers -3 (-112)
• Moneyline: Bears +144, 49ers -162
• Total: Over/Under 52.5 (-110/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Bears vs. Niners Week 17 details

The NFL Week 17 matchup between the 49ers and Bears at Levi's Stadium is scheduled for December 28, 2025.

• Who: Chicago Bears vs. San Francisco 49ers
• Date: Sunday, December 28, 2025
• Time: 8:20 PM ET/5:20PM PT
• Venue: Levi's Stadium

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Conclusion

We predict the 49ers, with a 61% win probability, will likely beat the Bears in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bears vs. 49ers matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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