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Bears vs. 49ers prediction: San Francisco favored to win ‘SNF’ Week 17 [2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Chicago Bears vs San Francisco 49ers predictions for NFL Sunday.
The San Francisco 49ers will face the Chicago Bears in NFL Week 17 action at Levi's Stadium on Sunday, starting at 8:20 PM ET.
Based on the latest simulations, Dimers' advanced NFL model predicts the 49ers as the most likely winner of the Bears vs. 49ers game.
This article offers further insights into this week's matchup, including projected touchdown scorers, best bets and player prop picks.
Bears vs. Niners prediction: Who will win ‘Sunday Night Football’?
Since our Bears-49ers predictions earlier in the week, we have simulated the result of Sunday's NFL matchup between the Bears and 49ers 10,000 times as part of our NFL predictions coverage.
Our famous predictive model currently gives the 49ers a 62% chance of beating the Bears in Week 17 of the NFL season. Our predicted final score has the 49ers winning 28-24.
According to our model, the bookies have got it right, and the Bears and 49ers each have a 50% chance of covering the spread, while the 51.5-point over/under has a 53% chance of going over.
To see win probabilities for every matchup this week, check out our expert NFL Week 17 straight up picks.
Bears vs. 49ers odds
We have sourced the best NFL odds in America for this game, which are listed here:
| Bet Type | Bears | 49ers |
|---|---|---|
| Spread | +3.5 (-118) | -3.5 (-102) |
| Moneyline | +160 | -190 |
| Total | o51.5 (-110) | u51.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Bears vs. 49ers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | 49ers -3.5 | -102 |
| Moneyline | Bears | +160 |
| Total | Over 51.5 | -110 |
According to our NFL best bets, the top play to make on this game is Over 51.5 total points.
Bears vs. 49ers TD scorers
Who will score a touchdown in Bears vs. 49ers?
According to our list of touchdown scorer predictions for today, Christian McCaffrey is most likely to score an anytime touchdown in Bears vs. 49ers.
Our projections give McCaffrey a 65.0% chance of scoring a TD at Levi's Stadium, while the running back is a 16.7% chance of scoring the first touchdown the game.
Anytime touchdown scorer predictions
Chicago Bears
| Player | Anytime TD Probability |
|---|---|
| D'Andre Swift (RB) | 38.7% |
| Kyle Monangai (RB) | 36.0% |
| DJ Moore (WR) | 31.3% |
| Colston Loveland (TE) | 27.0% |
| Luther Burden (WR) | 23.9% |
San Francisco 49ers
| Player | Anytime TD Probability |
|---|---|
| Christian McCaffrey (RB) | 65.0% |
| Jauan Jennings (WR) | 38.9% |
| Ricky Pearsall (WR) | 28.9% |
| Jake Tonges (TE) | 25.9% |
| Brian Robinson (RB) | 17.9% |
First touchdown scorer predictions
Chicago Bears
| Player | First TD Probability |
|---|---|
| D'Andre Swift (RB) | 7.6% |
| Kyle Monangai (RB) | 6.9% |
| DJ Moore (WR) | 5.8% |
| Colston Loveland (TE) | 4.9% |
| Luther Burden (WR) | 4.2% |
San Francisco 49ers
| Player | First TD Probability |
|---|---|
| Christian McCaffrey (RB) | 16.7% |
| Jauan Jennings (WR) | 7.8% |
| Ricky Pearsall (WR) | 5.4% |
| Jake Tonges (TE) | 4.8% |
| Brian Robinson (RB) | 3.1% |
Bears vs 49ers player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Bears and 49ers. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 17 games.
Quarterbacks
Of the starting quarterbacks, the Bears' Caleb Williams is projected for 229 passing yards. The 49ers' Brock Purdy is expected to throw for 256 yards.
| Player | Proj. Pass Yards |
|---|---|
| Caleb Williams (CHI) | 229 |
| Brock Purdy (SF) | 256 |
Bears rushing
| Player | Proj. Rush Yards |
|---|---|
| D'Andre Swift | 61 |
| Kyle Monangai | 48 |
| Caleb Williams | 22 |
49ers rushing
| Player | Proj. Rush Yards |
|---|---|
| Christian McCaffrey | 73 |
| Brian Robinson | 25 |
| Brock Purdy | 16 |
Bears receiving
| Player | Proj. Rec. Yards |
|---|---|
| DJ Moore | 51 |
| Luther Burden | 51 |
| Colston Loveland | 43 |
| Olamide Zaccheaus | 29 |
| Cole Kmet | 25 |
49ers receiving
| Player | Proj. Rec. Yards |
|---|---|
| Jauan Jennings | 60 |
| Ricky Pearsall | 48 |
| Christian McCaffrey | 46 |
| Jake Tonges | 23 |
| Kendrick Bourne | 22 |
Bears vs. Niners game-day updates and essential details
The NFL Week 17 action between the 49ers and Bears at Levi's Stadium is scheduled to commence at 8:20 PM ET.
- Who: Chicago Bears vs. San Francisco 49ers
- Date: Sunday, December 28, 2025
- Time: 8:20 PM ET/5:20PM PT
- Venue: Levi's Stadium
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Conclusion
We predict the 49ers, with a 62% win probability, will likely beat the Bears in Week 17 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Bears vs. 49ers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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