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Charlotte vs. App State prediction: Why Appalachian State is favored to win men's college basketball matchup [11/21/2025]
Get Charlotte vs App State predictions for college basketball Friday.

App State will square off with Charlotte, in what is expected to be a close Men's College Basketball game, at George M. Holmes Convocation Center on Friday, starting at 6:30PM ET.
Based on updated simulations, Dimers' proven college basketball model gives Appalachian State a slight edge with a 54% win probability over Charlotte.
This article offers further insights into Friday's Charlotte vs. App State matchup, including an expanded look at the predicted score, best bets and picks.
Charlotte vs. App State prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Friday's NCAA basketball game between Charlotte and App State 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Appalachian State a 54% chance of defeating Charlotte. Our predicted final score has Appalachian State winning 67-66.
According to our model, Charlotte (+1.5) has a 55% chance of covering the spread, while the over/under total of 132.5 points has a 53% chance of going over.
Charlotte vs. App State odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Charlotte | App State |
|---|---|---|
| Spread | +1.5 (-108) | -1.5 (-110) |
| Moneyline | +105 | -125 |
| Total | o132.5 (-110) | u132.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Charlotte vs. App State picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Charlotte +1.5 | -108 |
| Moneyline | Appalachian State | -125 |
| Total | Over 132.5 | -110 |
According to our best men's college basketball bets, the top play to make on this game is Charlotte +1.5 at the spread.
Charlotte vs. App State game-day updates and essential details
Friday's men's college basketball matchup between App State and Charlotte at George M. Holmes Convocation Center is scheduled to start at 6:30PM ET.
- Who: Charlotte vs. Appalachian State
- Date: Friday, November 21, 2025
- Time: 6:30PM ET/3:30PM PT
- Venue: George M. Holmes Convocation Center
Conclusion
We predict Appalachian State, with a 54% win probability, will likely beat Charlotte on Friday.
AI and automation have enhanced this article to quickly deliver accurate Charlotte vs. Appalachian State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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