Hornets vs. 76ers prediction: Why Philadelphia is favored to win Saturday's NBA matchup [10/25/2025]

The Philadelphia 76ers will take on the Charlotte Hornets in NBA action at Xfinity Mobile Arena on Saturday, commencing at 7:30PM ET.

Based on updated simulations and today’s injury updates, Dimers' proven NBA model predicts the 76ers as the most likely winner of the Hornets vs. 76ers game.

This prediction follows the latest NBA Injury Report, which suggests the 76ers lineup will feature stars like Tyrese Maxey, Joel Embiid and VJ Edgecombe, while the Hornets will look to LaMelo Ball, Miles Bridges and Brandon Miller.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Sixers vs. Sixers prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's NBA game between the Hornets and 76ers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the 76ers a 66% chance of beating the Hornets. Our predicted final score has the 76ers winning 120-115.

According to our model, the 76ers (-4.5) have a 51% chance of covering the spread, while the 236.5-point over/under has a 51% chance of staying under.

Hornets vs. 76ers odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Hornets vs. 76ers picks and best bet

Our predictions, matched with the current odds, reveal the top betting picks for this game, detailed in Dimers' best NBA bets for Saturday, crafted from expert modeling and analysis:

According to our NBA best bets, the top play to make on this game is 76ers moneyline.

Hornets vs. 76ers player props

NBA player props are an enjoyable way to wager on the Hornets vs. 76ers game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Xfinity Mobile Arena.

LaMelo Ball is expected to lead the Hornets with 25 points, 5 rebounds and 8 assists, while Tyrese Maxey is projected to have 28 points, 3 rebounds and 7 assists for the 76ers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Hornets prediction

Our model's projected player stats for the Hornets are:

76ers prediction

Projected points, rebounds, assists and three-pointers made for the 76ers:

Hornets vs. Sixers game-day updates and essential details

Saturday's action between the 76ers and Hornets at Xfinity Mobile Arena is scheduled to commence at 7:30PM ET.

• Who: Charlotte Hornets vs. Philadelphia 76ers
• Date: Saturday, October 25, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Xfinity Mobile Arena

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Conclusion

We predict the 76ers, with a 66% win probability, will likely beat the Hornets on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Hornets vs. 76ers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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