Charleston Southern vs. Winthrop prediction: Why Winthrop is favored to win men's college basketball matchup [1/7/2026]

Winthrop and Charleston Southern will meet in men's college basketball action at Winthrop Coliseum on Wednesday, starting at 6:30 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects Winthrop as the most likely winner of the Charleston Southern vs. Winthrop game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Charleston Southern vs. Winthrop prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Charleston Southern and Winthrop 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Winthrop a 77% chance of beating Charleston Southern. Our predicted final score has Winthrop winning 84-76.

According to our model, Charleston Southern (+9.5) has a 55% chance of covering the spread, while the over/under total of 165.5 points has a 54% chance of staying under.

Charleston Southern vs. Winthrop odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Charleston Southern vs. Winthrop picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: