Central Michigan vs. Saint Louis prediction: Saint Louis favored to win men's college basketball matchup [12/7/2025]

Saint Louis will square off with Central Michigan in men's college basketball action at Chaifetz Arena on Sunday, beginning at 3:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Saint Louis as the most likely winner of the Central Michigan vs. Saint Louis game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Central Michigan vs. Saint Louis prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between Central Michigan and Saint Louis 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Saint Louis a 98% chance of defeating Central Michigan. Our predicted final score has Saint Louis winning 91-65.

According to our model, Saint Louis (-24.5) has a 53% chance of covering the spread, while the 159.5-point over/under has a 53% chance of staying under.

Central Michigan vs. Saint Louis odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Central Michigan vs. Saint Louis picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: