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Panthers vs. Buccaneers prediction: Why Tampa Bay is favored to win in NFL Week 18 [2026]

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Written by Mac Douglass

Get Carolina Panthers vs Tampa Bay Buccaneers predictions for NFL Saturday.

Carolina Panthers-Tampa Bay Buccaneers Predictions and Game Preview.
Carolina Panthers vs. Tampa Bay Buccaneers NFL prediction for Saturday, January 3, 2026.

NFL Week 18 action continues on Saturday at 4:30 PM ET as the Carolina Panthers lock horns with the Tampa Bay Buccaneers at Raymond James Stadium.

Based on the latest simulations, Dimers' advanced NFL model predicts the Buccaneers as the most likely winner of the Panthers vs. Buccaneers game.

This article offers further insights into this week's matchup, including projected touchdown scorers, best bets and player prop picks.

Panthers vs. Bucs prediction: Who will win and cover?

Since our Panthers-Buccaneers predictions earlier in the week, we have simulated the result of Saturday's NFL matchup between the Panthers and Buccaneers 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Buccaneers a 61% chance of beating the Panthers in Week 18 of the NFL season. Our predicted final score has the Buccaneers winning 22-19.

According to our model, the bookmakers have got it right, and the Panthers and Buccaneers each have a 50% chance of covering the spread, while the 42.5-point over/under also has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 18 straight up picks.

Panthers vs. Buccaneers odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Panthers Buccaneers
Spread +3 (-114) -3 (-105)
Moneyline +138 -155
Total o42.5 (-115) u42.5 (-105)

All odds are correct at the time of publication and are subject to change.

Panthers vs. Buccaneers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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